oops ninja'd haha. @Joshless I don't think gemini eyebeams would immediately incinerate a Genesis Frog, no, but like you say neither do the Red Miles; they're a wide-reaching attack that just takes time to spread. if a midboss-level character like the Black Queen can eventually destroy a universe from the outside, I really don't see why a similarly powerful weapon couldn't at the very least wound one, and if you can wound something you can eventually kill it.

I really feel that universes in Homestuck being essentially just big, vulnerable creatures in a grand ecosystem is part of the point of them being frogs. it's not that you need to be an especially grand and powerful godlike being to kill them, you really just need to be the kind of particularly nasty person that would want to kill a giant harmless frog.