I'm a little surprised that so many people seem to be against Meowrails. But after reading over all the points brought up here and thinking it over... I'm still pro-Meowrails. But I'll concede that the relationship, like most of the trolls' relationships, is complicated.

I think that Nepeta genuinely enjoys Equius' company. When she spots him on her planet, she immediately rushes over to him. That doesn't seem like "I'm dreading being with this person" behavior to me.

People are right that Nepeta ends up doing a lot of emotional labor, but Equius' "This is f001ishness upon one hundred thousand prior, equally unsolicited f001ishnesses" comment implies that he's also doing emotional labor here too. Also, I'd wager that he probably taught her about several social norms that she would otherwise not learn as an autistic cave hermit.

Like Shadow The Hedgehog said, the relationship having flaws doesn't mean it's all bad, and I think Meowrails was a net benefit overall.