one thing i've already noticed is that pictures popping out of their frames - or literally images 'becoming animated' - is a recurring motif in the trailer. Dave pops out of his little voice call window to harass John, Dad uses a totally new move where he launches cakes out of sylladex cards, John popping out of a sprite-shaped hole in the wall could even count.

given Hussie is a writer here, I have every belief that they intend to push the cartoon medium in the same way the original Homestuck pushed the webcomic medium. i've even seen some people suggest that the cartoon could take the scott pilgrim anime route and pull off a twist divergence from the original comic's story, which would be a fascinating avenue for metanarrative and/or genre deconstructing elements as well if true.