yeah clip studio isnt exactly Made for spritework and can be a little awkward even if you do enable the grid but theres a metric ton of pixel brush assets you can download if you dont want to just copy default brush > turn anti-aliasing off lol. I havent used aesprite but i've only heard good things about it, but if you want to do other non-pixely things clip studio has that Versatility for ya. i guess its like a multitool that can do a lot of stuff well vs one specific tool that does that one thing REALLY well.